Alzheimer disease

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Prevalence (%) of clinical parameters based on data from 4 references describing 460 individuals







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Pubmed id number as a reference Organ system affected
Number of patients in the reference Percent affected patients (Between 0 and 1, eg. 0.1 = 10%)
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List of symptoms



Symptom/sign Organ system Percent affected Pubmed id Added on(yyyy-mm-dd) Edit/add reference
Dementia nervous 100 % 15534185 2013-08-22
Cerebral atrophy nervous 100 % 23303849 2016-12-22
Brain amyloid accumulation nervous 89 % 24179789 2019-02-07
Myoclonus nervous 61 % 15534185 2013-08-22
Limb dyspraxia nervous 44 % 15534185 2013-08-22
Anosmia nervous 23 % 16170073 2013-11-04
Hyperactive reflexes nervous 22 % 15534185 2013-08-22
Late visual disorientation nervous 17 % 15534185 2013-08-22
Seizures nervous 17 % 15534185 2013-08-22
Gait disturbances nervous 17 % 15534185 2013-08-22



List of references:


The natural history of Alzheimer disease: a longitudinal presymptomatic and symptomatic study of a familial cohort.
Alison K Godbolt, Lisa Cipolotti, Hilary Watt, Nick C Fox, John C Janssen, Martin N Rossor,



Archives of neurology - Nov 2004



Cerebral atrophy in mild cognitive impairment and Alzheimer disease: rates and acceleration.
Kelvin K Leung, Jonathan W Bartlett, Josephine Barnes, Emily N Manning, Sebastien Ourselin, Nick C Fox, ,



Neurology - Feb 2013



Amyloid imaging in cognitively normal individuals, at-risk populations and preclinical Alzheimer's disease.
Gaël Chételat, Renaud La Joie, Nicolas Villain, Audrey Perrotin, Vincent de La Sayette, Francis Eustache, Rik Vandenberghe,



NeuroImage. Clinical - 2013



Anosmia is very common in the Lewy body variant of Alzheimer's disease.
J M Olichney, C Murphy, C R Hofstetter, K Foster, L A Hansen, L J Thal, R Katzman,



Journal of neurology, neurosurgery, and psychiatry - Oct 2005