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Prevalence (%) of clinical parameters based on data from 2 references describing 122 individuals
Add new symptom/sign to this disease
| Pubmed id number as a reference | Organ system affected | ||
| Number of patients in the reference | Percent affected patients (Between 0 and 1, eg. 0.1 = 10%) | ||
| Please provide your name and contact information as a reference | |||
| Name | Institute | Phone number | Email address |
List of symptoms
| Symptom/sign | Organ system | Percent affected | Pubmed id | Added on(yyyy-mm-dd) | Edit/add reference |
| Optic atrophy | nervous | 100 % | 20837821 | 2011-10-18 | |
| Optic atrophy | nervous | 86 % | 20157015 | 2011-10-12 | |
| Hearing loss | nervous | 63 % | 20157015 | 2011-10-12 | |
| Ophthalmoplegia | nervous | 46 % | 20157015 | 2011-10-12 | |
| Myopathy | skeletal | 36 % | 20157015 | 2011-10-12 | |
| Ataxia | nervous | 30 % | 20157015 | 2011-10-12 | |
| Neuropathy | nervous | 30 % | 20157015 | 2011-10-12 |
List of references:
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Multi-system neurological disease is common in patients with OPA1 mutations.
P Yu-Wai-Man, P G Griffiths, G S Gorman, C M Lourenco, A F Wright, M Auer-Grumbach, A Toscano, O Musumeci, M L Valentino, L Caporali, C Lamperti, C M Tallaksen, P Duffey, J Miller, R G Whittaker, M R Baker, M J Jackson, M P Clarke, B Dhillon, B Czermin, J D Stewart, G Hudson, P Reynier, D Bonneau, W Marques, G Lenaers, R McFarland, R W Taylor, D M Turnbull, M Votruba, M Zeviani, V Carelli, L A Bindoff, R Horvath, P Amati-Bonneau, P F Chinnery,
Brain : a journal of neurology - Mar 2010