Hutchinson-Gilford progeria |
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Prevalence (%) of clinical parameters based on data from 3 references describing 42 individuals
Add new symptom/sign to this disease
| Pubmed id number as a reference | Organ system affected | ||
| Number of patients in the reference | Percent affected patients (Between 0 and 1, eg. 0.1 = 10%) | ||
| Please provide your name and contact information as a reference | |||
| Name | Institute | Phone number | Email address |
List of symptoms
| Symptom/sign | Organ system | Percent affected | Pubmed id | Added on(yyyy-mm-dd) | Edit/add reference |
| Alopecia | integumentary | 100 % | 18256394 | 2011-10-19 | |
| Failure to thrive | multi | 100 % | 18256394 | 2011-10-13 | |
| Micrognathia | skeletal | 100 % | 18256394 | 2012-01-19 | |
| Short stature | multi | 100 % | 18256394 | 2012-01-19 | |
| Weight loss | multi | 100 % | 18256394 | 2014-04-14 | |
| Arteriosclerosis | circulatory | 100 % | 11485857 | 2014-06-04 | |
| Skin pigmentation changes | integumentary | 93 % | 18256394 | 2011-10-13 | |
| Scleroderma | integumentary | 80 % | 18256394 | 2011-10-13 | |
| Osteoporosis | skeletal | 73 % | 18256394 | 2011-10-13 | |
| Sleeping with eyes open | nervous | 73 % | 18256394 | 2014-04-14 | |
| Circumoral cyanosis | circulatory | 60 % | 18256394 | 2014-04-14 | |
| Stroke | nervous | 60 % | 23179651 | 2014-06-04 | |
| Prominent veins | circulatory | 53 % | 18256394 | 2014-04-14 | |
| Hypertension | circulatory | 47 % | 18256394 | 2011-10-13 | |
| Contracture | skeletal | 47 % | 18256394 | 2012-01-19 | |
| Xerophthalmus | integumentary | 33 % | 18256394 | 2011-10-13 | |
| Cardiac conduction defect | circulatory | 33 % | 18256394 | 2011-10-13 | |
| Long QT | circulatory | 33 % | 18256394 | 2014-04-14 | |
| Kyphosis | skeletal | 20 % | 18256394 | 2011-10-13 |
List of references:
Phenotype and course of Hutchinson-Gilford progeria syndrome.
Melissa A Merideth, Leslie B Gordon, Sarah Clauss, Vandana Sachdev, Ann C M Smith, Monique B Perry, Carmen C Brewer, Christopher Zalewski, H Jeffrey Kim, Beth Solomon, Brian P Brooks, Lynn H Gerber, Maria L Turner, Demetrio L Domingo, Thomas C Hart, Jennifer Graf, James C Reynolds, Andrea Gropman, Jack A Yanovski, Marie Gerhard-Herman, Francis S Collins, Elizabeth G Nabel, Richard O Cannon, William A Gahl, Wendy J Introne,
The New England journal of medicine - Feb 2008
Smooth muscle cell depletion and collagen types in progeric arteries.
W E Stehbens, B Delahunt, T Shozawa, E Gilbert-Barness,
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology - 2001
Imaging characteristics of cerebrovascular arteriopathy and stroke in Hutchinson-Gilford progeria syndrome.
V M Silvera, L B Gordon, D B Orbach, S E Campbell, J T Machan, N J Ullrich,
AJNR. American journal of neuroradiology - May 2013