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Prevalence (%) of clinical parameters based on data from 1 references describing 38 individuals
Add new symptom/sign to this disease
| Pubmed id number as a reference | Organ system affected | ||
| Number of patients in the reference | Percent affected patients (Between 0 and 1, eg. 0.1 = 10%) | ||
| Please provide your name and contact information as a reference | |||
| Name | Institute | Phone number | Email address |
List of symptoms
| Symptom/sign | Organ system | Percent affected | Pubmed id | Added on(yyyy-mm-dd) | Edit/add reference |
| Spasticity | nervous | 100 % | 19805727 | 2019-12-10 | |
| Hyperactive reflexes | nervous | 100 % | 19805727 | 2019-12-10 | |
| Babinski's sign | nervous | 100 % | 19805727 | 2019-12-10 | |
| Mental retardation | nervous | 79 % | 19805727 | 2019-12-10 | |
| Corpus callosum thining | nervous | 79 % | 19805727 | 2019-12-10 | |
| Neuropathy | nervous | 65 % | 19805727 | 2019-12-10 | |
| White matter hyperintensities | nervous | 52 % | 19805727 | 2019-12-10 | |
| Muscle atrophy | skeletal | 49 % | 19805727 | 2019-12-10 | |
| Dysarthria | nervous | 49 % | 19805727 | 2019-12-10 | |
| Cerebral atrophy | nervous | 44 % | 19805727 | 2019-12-10 | |
| Ataxia | nervous | 37 % | 19805727 | 2019-12-10 | |
| Retinitis pigmentosa | nervous | 33 % | 19805727 | 2019-12-10 | |
| Pallesthesia | nervous | 27 % | 19805727 | 2019-12-10 | |
| Cerebellar atrophy | nervous | 26 % | 19805727 | 2019-12-10 | |
| Hearing loss | nervous | 18 % | 19805727 | 2019-12-10 |
List of references:
SPG15 is the second most common cause of hereditary spastic paraplegia with thin corpus callosum.
C Goizet, A Boukhris, D Maltete, L Guyant-Maréchal, J Truchetto, E Mundwiller, S Hanein, P Jonveaux, F Roelens, J Loureiro, E Godet, S Forlani, J Melki, M Auer-Grumbach, J C Fernandez, P Martin-Hardy, I Sibon, G Sole, I Orignac, C Mhiri, P Coutinho, A Durr, A Brice, G Stevanin,
Neurology - Oct 2009