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Prevalence (%) of clinical parameters based on data from 2 references describing 63 individuals
Add new symptom/sign to this disease
| Pubmed id number as a reference | Organ system affected | ||
| Number of patients in the reference | Percent affected patients (Between 0 and 1, eg. 0.1 = 10%) | ||
| Please provide your name and contact information as a reference | |||
| Name | Institute | Phone number | Email address |
List of symptoms
| Symptom/sign | Organ system | Percent affected | Pubmed id | Added on(yyyy-mm-dd) | Edit/add reference |
| Developmental delay | nervous | 100 % | 9568915 | 2011-12-05 | |
| Leukodystrophy | nervous | 100 % | 3354621 | 2011-12-05 | |
| Macrocephaly | nervous | 92 % | 9568915 | 2011-12-05 | |
| Nystagmus | nervous | 88 % | 9568915 | 2011-12-05 | |
| Dysphagia | nervous | 80 % | 9568915 | 2011-12-05 | |
| Seizures | nervous | 63 % | 9568915 | 2011-12-05 | |
| Optic atrophy | nervous | 58 % | 9568915 | 2011-12-05 | |
| Vomiting | nervous | 47 % | 9568915 | 2011-12-05 |
List of references:
The clinical course of Canavan disease.
E C Traeger, I Rapin,
Pediatric neurology - Mar 1998
Aspartoacylase deficiency and N-acetylaspartic aciduria in patients with Canavan disease.
R Matalon, K Michals, D Sebesta, M Deanching, P Gashkoff, J Casanova,
American journal of medical genetics - Feb 1988