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Prevalence (%) of clinical parameters based on data from 3 references describing 145 individuals
Add new symptom/sign to this disease
| Pubmed id number as a reference | Organ system affected | ||
| Number of patients in the reference | Percent affected patients (Between 0 and 1, eg. 0.1 = 10%) | ||
| Please provide your name and contact information as a reference | |||
| Name | Institute | Phone number | Email address |
List of symptoms
| Symptom/sign | Organ system | Percent affected | Pubmed id | Added on(yyyy-mm-dd) | Edit/add reference |
| Optic atrophy | nervous | 100 % | 2858640 | 2011-10-18 | |
| Optic atrophy | nervous | 100 % | 7735876 | 2011-10-05 | |
| Tremor | nervous | 30 % | 11523562 | 2011-10-05 | |
| Cardiac conduction defect | circulatory | 25 % | 2858640 | 2011-10-05 | |
| Neuropathy | nervous | 20 % | 11523562 | 2011-10-05 | |
| Kyphosis | skeletal | 15 % | 11523562 | 2011-10-05 | |
| Headache | nervous | 9 % | 11523562 | 2011-10-05 | |
| Seizures | nervous | 7 % | 11523562 | 2011-10-05 | |
| Multiple sclerosis | nervous | 6 % | 7735876 | 2011-10-05 | |
| Multiple sclerosis | nervous | 4 % | 11523562 | 2011-10-05 | |
| Parkinsonism | nervous | 2 % | 11523562 | 2011-10-05 |
List of references:
Pre-excitation syndrome and Leber's hereditary optic neuroretinopathy.
E Nikoskelainen, O Wanne, M Dahl,
Lancet (London, England) - Mar 1985
The clinical features of Leber's hereditary optic neuropathy defined by the presence of a pathogenic mitochondrial DNA mutation.
P Riordan-Eva, M D Sanders, G G Govan, M G Sweeney, J Da Costa, A E Harding,
Brain : a journal of neurology - Apr 1995
Leber hereditary optic neuropathy: clinical and molecular genetic findings.
K Huoponen,
Neurogenetics - Jul 2001