Sickle cell anemia

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Prevalence (%) of clinical parameters based on data from 9 references describing 3,057 individuals

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Pubmed id number as a reference Organ system affected
Number of patients in the reference Percent affected patients (Between 0 and 1, eg. 0.1 = 10%)
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List of symptoms

Symptom/sign Organ system Percent affected Pubmed id Added on(yyyy-mm-dd) Edit/add reference
Cor pulmonale respiratory 100 % 7148875 2012-05-09
Acute chest syndrome multi 67 % 10861320 2011-10-27
Anemia circulatory 55 % 19500105 2011-10-27
Asplenia circulatory 45 % 7718896 2011-10-27
Priapism urinary 36 % 12460353 2011-10-27
Pulmonary hypertension circulatory 32 % 14985486 2011-10-27
Cholelithiasis digestive 31 % 10636979 2011-10-27
Stroke nervous 28 % 19500105 2011-10-27
Cor pulmonale respiratory 14 % 13410950 2012-05-09
Osteonecrosis skeletal 9 % 1944426 2011-10-27

List of references:

Pulmonary hypertension and cor pulmonale in the sickle hemoglobinopathies.
F S Collins, E P Orringer,

The American journal of medicine - Dec 1982

Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group.
E P Vichinsky, L D Neumayr, A N Earles, R Williams, E T Lennette, D Dean, B Nickerson, E Orringer, V McKie, R Bellevue, C Daeschner, E A Manci,

The New England journal of medicine - Jun 2000

Silent infarcts in young children with sickle cell disease.
Janet L Kwiatkowski, Robert A Zimmerman, Avrum N Pollock, Wendy Seto, Kim Smith-Whitley, Justine Shults, Anne Blackwood-Chirchir, Kwaku Ohene-Frempong,

British journal of haematology - Aug 2009

Functional asplenia in hemoglobin SC disease.
P A Lane, J L O'Connell, J L Lear, Z R Rogers, G M Woods, K L Hassell, D L Wethers, D W Luckey, G R Buchanan,

Blood - Apr 1995

Priapism in sickle-cell disease; incidence, risk factors and complications - an international multicentre study.
A B Adeyoju, A B K Olujohungbe, J Morris, A Yardumian, D Bareford, A Akenova, O Akinyanju, K Cinkotai, P H O'Reilly,

BJU international - Dec 2002

Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Mark T Gladwin, Vandana Sachdev, Maria L Jison, Yukitaka Shizukuda, Jonathan F Plehn, Karin Minter, Bernice Brown, Wynona A Coles, James S Nichols, Inez Ernst, Lori A Hunter, William C Blackwelder, Alan N Schechter, Griffin P Rodgers, Oswaldo Castro, Frederick P Ognibene,

The New England journal of medicine - Feb 2004

Gallstones in sickle cell disease: observations from The Jamaican Cohort study.
T M Walker, I R Hambleton, G R Serjeant,

The Journal of pediatrics - Jan 2000

The relationship between pulmonary infarction, cor pulmonale and the sickle states.

The American journal of medicine - Apr 1957

Sickle cell disease as a cause of osteonecrosis of the femoral head.
P F Milner, A P Kraus, J I Sebes, L A Sleeper, K A Dukes, S H Embury, R Bellevue, M Koshy, J W Moohr, J Smith,

The New England journal of medicine - Nov 1991