Warning: simplexml_load_file(http://api.omim.org/api/entry?mimNumber=604901&include=text:description&apiKey=nF1Y-SFBSLOjxS6VQpq65A): failed to open stream: HTTP request failed! HTTP/1.1 400 in /customers/0/2/d/mitodb.com/httpd.www/symptoms.php on line 485 Warning: simplexml_load_file(): I/O warning : failed to load external entity "http://api.omim.org/api/entry?mimNumber=604901&include=text:description&apiKey=nF1Y-SFBSLOjxS6VQpq65A" in /customers/0/2/d/mitodb.com/httpd.www/symptoms.php on line 485 Mito DB


North American Indian Childhood Cirrhosis
NAIC

Contact us
 
Return to database


We were unfortunately unable to download the information for this disease from OMIM.



Prevalence of clinical parameters (%)







Add new symptom/sign to this disease

Select symptom from list or write it in the box
Pubmed id number as a reference Organ system affected
Number of patients in the reference Percent affected patients (Between 0 and 1, eg. 0.1 = 10%)
Please provide your name and contact information as a reference
Name Institute Phone number Email address


List of symptoms



Symptom/sign Organ system Percent affected Pubmed id Added on(yyyy-mm-dd) Edit/add reference
Hepatomegaly circulatory 90 % 11045837 2015-04-01
Portal hypertension circulatory 90 % 11045837 2015-04-01
Increased alkaline phosphatase circulatory 90 % 11045837 2015-04-01
Increased blood transaminase circulatory 90 % 11045837 2015-04-01
Increased blood gammaglutamyltransferase circulatory 90 % 11045837 2015-04-01
Coagulopathy circulatory 90 % 11045837 2015-04-01
Heart murmur circulatory 87 % 11045837 2015-04-01
Telangiectasia circulatory 77 % 11045837 2015-04-01
Otitis media nervous 77 % 11045837 2015-04-01
Bronchial hyperactivity respiratory 77 % 11045837 2015-04-01
Jaundice circulatory 70 % 11045837 2015-04-01
Splenomegaly circulatory 67 % 11045837 2015-04-01
Pruritus integumentary 53 % 11045837 2015-04-01
Epistaxis respiratory 53 % 11045837 2015-04-01
Variceal bleeding digestive 50 % 11045837 2015-04-01
Ascites digestive 27 % 11045837 2015-04-01
Liver failure digestive 20 % 11045837 2015-04-01
Short stature skeletal 13 % 11045837 2015-04-01
Cardiac structural defects circulatory 7 % 11045837 2015-04-01
Spontaneous bacterial peritonitis digestive 6 % 11045837 2015-04-01
Hematemesis digestive 3 % 11045837 2015-04-01



List of references:


North American Indian cirrhosis in children: a review of 30 cases.
E Drouin, P Russo, B Tuchweber, G Mitchell, A Rasquin-Weber,

North American Indian childhood cirrhosis (NAIC) is a distinct, rapidly evolving form of familial cholestasis found in aboriginal children from northwestern Quebec. This is a retrospective review of the 30 patients treated in Quebec since the discovery of NAIC in 1970.

Journal of pediatric gastroenterology and nutrition - Oct 2000


Warning: Use of undefined constant jump - assumed 'jump' (this will throw an Error in a future version of PHP) in /customers/0/2/d/mitodb.com/httpd.www/symptoms.php on line 715