Frontotemporal dementia and/or amyotrophic lateral sclerosis-4 |
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Prevalence (%) of clinical parameters based on data from 1 references describing 13 individuals
Add new symptom/sign to this disease
| Pubmed id number as a reference | Organ system affected | ||
| Number of patients in the reference | Percent affected patients (Between 0 and 1, eg. 0.1 = 10%) | ||
| Please provide your name and contact information as a reference | |||
| Name | Institute | Phone number | Email address |
List of symptoms
| Symptom/sign | Organ system | Percent affected | Pubmed id | Added on(yyyy-mm-dd) | Edit/add reference |
| Dementia | nervous | 69 % | 26674655 | 2020-01-24 | |
| Cerebral atrophy | nervous | 69 % | 26674655 | 2020-01-24 | |
| Apathy | nervous | 62 % | 26674655 | 2020-01-24 | |
| Behavioural disinhibition | nervous | 54 % | 26674655 | 2020-01-24 | |
| Psychiatric symptom | nervous | 54 % | 26674655 | 2020-01-24 | |
| Motor neuron degeneration | nervous | 50 % | 26674655 | 2020-01-24 | |
| Compulsive behavior | nervous | 46 % | 26674655 | 2020-01-24 | |
| Agitation | nervous | 46 % | 26674655 | 2020-01-24 | |
| Word retrieval difficulties | nervous | 46 % | 26674655 | 2020-01-24 | |
| Hyperactive reflexes | nervous | 46 % | 26674655 | 2020-01-24 | |
| Dysphagia | nervous | 46 % | 26674655 | 2020-01-24 | |
| Orientation difficulties | nervous | 38 % | 26674655 | 2020-01-24 | |
| Babinski's sign | nervous | 38 % | 26674655 | 2020-01-24 | |
| Hyperorality | nervous | 31 % | 26674655 | 2020-01-24 | |
| Rigidity | nervous | 30 % | 26674655 | 2020-01-24 | |
| Spasticity | nervous | 30 % | 26674655 | 2020-01-24 | |
| Fasciculations | nervous | 30 % | 26674655 | 2020-01-24 | |
| Muscle atrophy | nervous | 30 % | 26674655 | 2020-01-24 | |
| Dysarthria | nervous | 30 % | 26674655 | 2020-01-24 | |
| Repetitive movements | nervous | 23 % | 26674655 | 2020-01-24 | |
| Tremor | nervous | 15 % | 26674655 | 2020-01-24 | |
| Bradykinesia | nervous | 15 % | 26674655 | 2020-01-24 | |
| Prosopagnosia | nervous | 8 % | 26674655 | 2020-01-24 | |
| Psychosis | nervous | 8 % | 26674655 | 2020-01-24 | |
| Dyspnoea | respiratory | 8 % | 26674655 | 2020-01-24 |
List of references:
Clinical features of TBK1 carriers compared with C9orf72, GRN and non-mutation carriers in a Belgian cohort.
Sara Van Mossevelde, Julie van der Zee, Ilse Gijselinck, Sebastiaan Engelborghs, Anne Sieben, Tim Van Langenhove, Jan De Bleecker, Jonathan Baets, Mathieu Vandenbulcke, Koen Van Laere, Sarah Ceyssens, Marleen Van den Broeck, Karin Peeters, Maria Mattheijssens, Patrick Cras, Rik Vandenberghe, Peter De Jonghe, Jean-Jacques Martin, Peter P De Deyn, Marc Cruts, Christine Van Broeckhoven, ,
Brain : a journal of neurology - Feb 2016